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137 Among alcoholic individuals, GSTM1 null genetic variant carriers are at an elevated risk of developing alcoholic liver disease, 138 while studies indicate that in non-alcoholic fatty liver disease, individuals with the Val/Val genotype of GSTP1 and null genotype of GSTT1/GSTM1 null genotype have a higher susceptibility to the disease

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The post-translational modification that results in the shift in position of the different isoforms has not been described